Troy, John, PhD



Troy, John, PhD




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Biomedical Engineering


Tech E372 Evanston

Areas of Research

Cell Biology, Signal Transduction

NU Scholar Profile

Recent Publications on PubMed

Current Research

Current Research

<strong>Retinal information processing in higher mammals</strong>
The current focus of the laboratory is to understand how visual images are encoded in higher mammals by the activity patterns of the retina's ganglion cells. Ganglion cells provide the only link between the retina and the brain and, therefore, all visual information must pass along their axons to higher visual centers. It has been known for a number years that there are many varieties of retinal ganglion cell, each type signaling a different visual characteristic. Using the tools of electrophysiology, anatomy and modeling we have made significant strides towards elucidating the message carried by the most common varieties of ganglion cell. Nonetheless, there remain many challenges ahead.
We have recently been studying how visual information is encoded by ensembles of retinal ganglion cells. It has been known for a few decades that the firing of neighboring ganglion cells is correlated, but the significance of having the some information carried to the brain in common by more than one ganglion cell is not well understood. The investigation of this question is of great importance, because its resolution stands to change our view of neural coding by the retina.
We also attempting to develop new nanoscale probes that can be used to record from and electrically stimulate single neurons.